Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 402
interventional 209
Observational 172
Registry 21

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 70
Drug|placebo 41
Other 31
Procedure 12
Device 10
Behavioral 7
Diagnostic Test 5
Dietary Supplement 5
Biological 4
Drug|Other 4
Biological|Other 3
Dietary Supplement|placebo 3
Behavioral|Drug 2
Device|Other 2
Drug|Procedure 2
Behavioral|Other 1
Biological|placebo 1
Combination Product 1
Combination Product|Drug 1
Diagnostic Test|Other 1
Drug|Other|Procedure 1
Drug|placebo|Procedure 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 47
China 16
NA 16
France 12
Germany 11
Egypt 7
Canada 6
Italy 6
Thailand 6
Brazil 5
Netherlands 5
Greece 4
Spain 4
Bangladesh 3
India 3
Switzerland 3
United Kingdom 3
Argentina 2
Ghana 2
Japan 2
Kenya 2
Pakistan 2
Peru 2
Singapore 2
United States|Canada 2
Argentina|Australia|Austria|Belgium|Brazil|Canada|Chile|Czech Republic|Denmark|Egypt|Finland|France 1
Australia 1
Australia|Belgium|Canada|Czech Republic|Finland|France|Spain 1
Austria 1
Austria|Belgium|Poland|Portugal|United States|Argentina|Australia|Brazil|Canada|Chile|Czechia|France|Germany|Hong Kong|Israel|Italy|Japan|Korea, Republic of|Netherlands|South Africa|Spain|Switzerland|Taiwan|United Kingdom 1
Belgium 1
Belgium|Netherlands 1
Burkina Faso|Gambia 1
Colombia 1
Czechia 1
Denmark|Finland|Iceland|Norway 1
Finland 1
France|Germany 1
Georgia|Kazakhstan|Moldova, Republic of|Ukraine|Uzbekistan 1
Germany|Greece 1
Hungary 1
Indonesia 1
Iran, Islamic Republic of 1
Israel 1
Jordan 1
Mexico 1
Norway 1
Panama 1
Saudi Arabia 1
Taiwan 1
Turkey 1
United States|Argentina|Australia|Belgium|Brazil|Bulgaria|Canada|Croatia|Czechia|Finland|France|Germany|Hungary|India|Israel|Korea, Republic of|Netherlands|New Zealand|Peru|Russian Federation|Serbia|Spain|Taiwan|United Kingdom 1
United States|Australia|Austria|Belgium|Canada|Czech Republic|Finland|Germany|Israel|Italy|Japan|Netherlands|New Zealand|Puerto Rico|Spain|Sweden|United Kingdom 1
United States|Australia|Chile|France|Germany|Italy|Mexico|Poland|Slovakia|Switzerland|United Kingdom 1
United States|Belgium|Canada|Finland|France|Germany|Puerto Rico|Spain|United Kingdom 1
United States|Belgium|Hungary|Netherlands|Poland 1
United States|Canada|France|Germany|Spain 1
United States|Canada|Malaysia|Thailand 1
United States|France 1
United States|France|Argentina|Australia|Austria|Belgium|Brazil|Canada|Chile|Czechia|Estonia|Finland|Germany|Greece|Hong Kong|Hungary|India|Israel|Korea, Republic of|Latvia|Malaysia|Netherlands|New Zealand|Portugal|Puerto Rico|Romania|Russian Federation|Slovenia|South Africa|Spain|Sweden|Taiwan|Thailand|United Kingdom 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 140
2 9
3 10
5 5
6 4
7 2
8 1
10 2
12 4
13 4
15 1
16 2
17 2
18 2
24 1
26 1
27 1
31 1
34 2
35 1
42 1
43 1
47 1
51 1
52 2
62 1
71 1
87 1
93 1
145 1
161 1
251 1
390 1

Phase

Phase Study_Count
N/A 86
Phase 3 39
Phase 2 34
Phase 4 30
Phase 2/Phase 3 7
Phase 1 6
Phase 1/Phase 2 6
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 27
2 132
3 19
4 8
5 1
6 2
12 1
NA 19

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 8 15.00 10.00000 10.00000 20.0000 50.0000 4.0000 9.0000
1st Qu. 8 77.00 36.50000 13.75000 38.0000 70.0000 120.0000 51.2500
Median 8 146.50 41.00000 21.50000 64.0000 150.0000 322.5000 125.0000
Mean 8 9489.86 39.66667 97.66667 176.5312 331.2857 876.6053 315.1333
3rd Qu. 8 577.50 48.50000 47.25000 190.0000 200.0000 675.0000 211.2500
Max. 8 530000.00 60.00000 466.00000 1415.0000 1579.0000 12500.0000 2040.0000

Trial Group Type

group_type Group_Count
Experimental 174
Active Comparator 97
Placebo Comparator 78
No Intervention 36
Other 19
NA 19
Sham Comparator 5

Intervention Model

intervention_model Study_Count
Parallel Assignment 156
Single Group Assignment 36
Crossover Assignment 6
Factorial Assignment 5
Sequential Assignment 3
NA 3

Primary Purpose

primary_purpose Study_Count
Treatment 142
Prevention 21
Diagnostic 17
Health Services Research 9
Screening 6
Supportive Care 4
NA 4
Basic Science 3
Other 3

Observational Studies

Studies by Country

Country Study_Count
United States 40
China 19
NA 14
Germany 12
France 11
Taiwan 6
United Kingdom 6
Egypt 5
Italy 5
Sweden 4
Czechia 3
Greece 3
Israel 3
Belgium 2
Canada 2
Hong Kong 2
India 2
Korea, Republic of 2
Lithuania 2
Singapore 2
Thailand 2
Turkey 2
United States|Canada 2
Argentina 1
Bangladesh 1
Belgium|France 1
Belgium|France|Germany|Italy|Netherlands 1
Belgium|France|Spain|Switzerland 1
Canada|New Zealand|United Kingdom 1
Denmark 1
Finland 1
France|Italy|Switzerland|United Kingdom 1
France|Spain 1
Indonesia|Thailand|Vietnam 1
Malaysia 1
Pakistan 1
Slovakia 1
South Africa 1
Suriname 1
Switzerland 1
United States|Australia|Canada|Colombia|Netherlands 1
United States|Canada|Israel|Singapore|United Kingdom 1
United States|Greece 1
United States|Sweden 1

Sites per Study

Site_count Study_Count
1 127
2 13
3 5
4 2
5 8
6 1
7 4
9 1
13 1
14 2
15 1
16 1
19 1
20 1
21 1
24 1
27 1
52 1

Enrollment Metrics

Measure Observational
Min 4.000
1st Qu 77.000
Median 200.000
Mean 2196.918
3rd Qu 601.500
Max 252245.000

Observation Model

observational_model Study_Count
Cohort 105
Case-Only 25
Case-Control 18
Other 10
Case Control 9
NA 4
Defined Population 1

Time Perspective

time_perspective Study_Count
Prospective 143
Retrospective 17
Other 5
Cross-Sectional 4
NA 2
Cross-Sectional, Retrospective/Prospective 1

Registries

Studies by Country

Country Study_Count
NA 5
China 4
Norway 3
France 2
Belgium 1
Czechia 1
Egypt 1
Germany 1
Korea, Republic of 1
Thailand 1
United States 1

Sites per Study

Site_count Study_Count
1 18
3 2
4 1

Enrollment Metrics

Measure Registries
Min 1.000
1st Qu 60.000
Median 175.000
Mean 1755.952
3rd Qu 458.000
Max 20000.000

Registry Model

observational_model Study_Count
Cohort 9
Case-Control 8
Case-Only 3
Other 1

Time Perspective

time_perspective Study_Count
Prospective 19
Cross-Sectional 1
Other 1

Follow-up

target_duration Study_Count
1 Month 4
1 Day 3
1 Year 3
3 Months 3
28 Days 2
12 Months 1
2 Months 1
20 Years 1
4 Weeks 1
7 Days 1
90 Days 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04459572 As an Early Indicator Biomarker of Prognosis and Mortality in Children With Sepsis and Septic Shock: suPAR https://ClinicalTrials.gov/show/NCT04459572 Completed Ege University 2019-09-27
NCT02376842 Study of an Electronic Health Record-embedded Severe Sepsis Early Warning Alert https://ClinicalTrials.gov/show/NCT02376842 Completed Stanford University 2015-03-31
NCT02163174 Pentoxifylline and Late Onset Sepsis in Preterm Infants https://ClinicalTrials.gov/show/NCT02163174 Completed Mansoura University 2013-02-28
NCT03403530 Efficacy of IgM Rich Immunoglobulin With Antibiotics for Bacterial Sepsis in Very Low Birth Weight Preterm Neonates https://ClinicalTrials.gov/show/NCT03403530 Completed Sir Takhtasinhji General Hospital 2018-06-30
NCT03371680 Kinetics of Surfactant Proteins, Phosphatidylcholine and Body Water in Intensive Care Unit (ICU) https://ClinicalTrials.gov/show/NCT03371680 Completed University of Padova 2013-12-31
NCT03821038 Recombinant Interleukin-7 (CYT107) to Restore Absolute Lymphocyte Counts in Sepsis Patients https://ClinicalTrials.gov/show/NCT03821038 Recruiting Revimmune 2020-06-30
NCT03332225 A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis https://ClinicalTrials.gov/show/NCT03332225 Active, not recruiting Hellenic Institute for the Study of Sepsis 2019-12-03
NCT03295825 Heparin Binding Protein in Early Sepsis Diagnosis https://ClinicalTrials.gov/show/NCT03295825 Completed Hellenic Institute for the Study of Sepsis 2018-06-30
NCT03295162 Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis https://ClinicalTrials.gov/show/NCT03295162 Completed Ain Shams University 2017-03-01
NCT03277677 The Effect of Fluid Resuscitation With 0.9% Sodium Chloride Versus Balanced Crystalloid Solution on Renal Function of Sepsis Patients https://ClinicalTrials.gov/show/NCT03277677 Recruiting Chulalongkorn University 2018-07-01
NCT03275090 The Effects of Two Different Intravenous Lipid Emulsions on the Outcomes of Preterm Infants With Sepsis https://ClinicalTrials.gov/show/NCT03275090 Completed Mansoura University Children Hospital 2017-01-02
NCT03258684 Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT03258684 Completed Zhujiang Hospital 2019-02-02
NCT03256461 Lactate Clearance Goal-directed Therapy in Sepsis https://ClinicalTrials.gov/show/NCT03256461 Recruiting Nanfang Hospital of Southern Medical University 2020-12-31
NCT03246893 Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis Patients https://ClinicalTrials.gov/show/NCT03246893 Recruiting Mahidol University 2020-04-30
NCT03238742 The Efficacy of Xuebijing Injection on Sepsis https://ClinicalTrials.gov/show/NCT03238742 Recruiting Southeast University, China 2019-12-31
NCT03237728 Study of Multiple-dose Kukoamine B Mesilate in Sepsis Patients https://ClinicalTrials.gov/show/NCT03237728 Completed Tianjin Chasesun Pharmaceutical Co., LTD 2019-09-25
NCT03199547 Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Death https://ClinicalTrials.gov/show/NCT03199547 Recruiting London School of Hygiene and Tropical Medicine 2020-12-31
NCT03175328 CRRT Timing in Sepsis-associated AKI in ICU https://ClinicalTrials.gov/show/NCT03175328 Recruiting Second Affiliated Hospital of Guangzhou Medical University 2022-02-28
NCT03152474 Adrenal Cortical Function and Vitamin A Deficiency in Sepsis https://ClinicalTrials.gov/show/NCT03152474 Completed Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 2000-01-31
NCT03137446 Restrictive Intravenous Fluids Trial in Sepsis https://ClinicalTrials.gov/show/NCT03137446 Completed Rhode Island Hospital 2018-03-30
NCT03129542 Midodrine Hydrochloride in Early Sepsis https://ClinicalTrials.gov/show/NCT03129542 Recruiting Mayo Clinic 2020-07-31
NCT03078335 Glove-based Care in the NICU to Prevent Late Onset Sepsis https://ClinicalTrials.gov/show/NCT03078335 Completed Hamilton Health Sciences Corporation 2018-06-01
NCT03068741 Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP) https://ClinicalTrials.gov/show/NCT03068741 Recruiting Sunnybrook Health Sciences Centre 2024-03-31
NCT03048994 Glutamine Supplementation in Critically Ill Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT03048994 Completed Changi General Hospital 2013-06-30
NCT03019965 Efficacy of Betalactam Antibiotics in Prolonged Infusion Compared to Intermittent in Pediatric Patients With Sepsis https://ClinicalTrials.gov/show/NCT03019965 Completed Coordinación de Investigación en Salud, Mexico 2019-07-30
NCT02972827 Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02972827 Recruiting Santa Barbara Cottage Hospital 2020-05-31
NCT02960854 A Study of Nivolumab Safety and Pharmacokinetics in Patients With Severe Sepsis or Septic Shock. https://ClinicalTrials.gov/show/NCT02960854 Completed Bristol-Myers Squibb 2018-01-05
NCT02959229 Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis https://ClinicalTrials.gov/show/NCT02959229 Completed Ain Shams University 2015-12-31
NCT02954926 Intravenous Immunoglobulin in Prevention of Preterm Neonatal Sepsis https://ClinicalTrials.gov/show/NCT02954926 Completed Hormozgan University of Medical Sciences 2016-10-31
NCT02927054 Effect of Education on Resident Physician Knowledge of Sepsis https://ClinicalTrials.gov/show/NCT02927054 Completed University of Utah 2016-09-30
NCT02899143 Short-course Antimicrobial Therapy in Sepsis https://ClinicalTrials.gov/show/NCT02899143 Recruiting Ospedale Santa Maria delle Croci 2019-12-31
NCT02898961 Impact of 30 mg/kg Amikacin and 8 mg/kg Gentamicin on Serum Concentrations in Critically Ill Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02898961 Completed Centre Hospitalier Universitaire de Nīmes 2015-02-28
NCT02891174 The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy https://ClinicalTrials.gov/show/NCT02891174 Completed University of Michigan 2018-03-31
NCT02883595 Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis https://ClinicalTrials.gov/show/NCT02883595 Completed Sun Yat-sen University 2016-09-30
NCT02871544 Predictive Value of Dynamic Combination of BNP and NGAL for the Prognosis of Patients With Sepsis https://ClinicalTrials.gov/show/NCT02871544 Completed Southeast University, China 2016-02-29
NCT02867267 The Efficacy and Safety of Ta1 for Sepsis https://ClinicalTrials.gov/show/NCT02867267 Recruiting Sun Yat-sen University 2020-12-31
NCT02837731 Fluid Responsiveness Evaluation in Sepsis-associated Hypotension https://ClinicalTrials.gov/show/NCT02837731 Completed Cheetah Medical Inc. 2019-03-31
NCT02820675 Quality Improvement in Infection COntrol and Sepsis Management in MOdel Regions https://ClinicalTrials.gov/show/NCT02820675 Recruiting Center for Sepsis Control and Care, Germany 2019-07-31
NCT02794025 The Effect of Esmolol on Clinical Prognosis of Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02794025 Completed Fujian Provincial Hospital 2013-01-31
NCT02789995 Dysfunctions of Human Muscle Stem Cells in Sepsis https://ClinicalTrials.gov/show/NCT02789995 Completed Institut Pasteur 2018-06-28
NCT02748382 Fluids in Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02748382 Completed McMaster University 2017-08-19
NCT02747121 Effects of External Inspection on Sepsis Detection and Treatment https://ClinicalTrials.gov/show/NCT02747121 Recruiting Norwegian Board of Health Supervision 2020-12-31
NCT02734550 (1,3)-β-D-glucan Based Diagnosis of Invasive Candida Infection in Sepsis https://ClinicalTrials.gov/show/NCT02734550 Completed Center for Sepsis Control and Care, Germany 2019-08-22
NCT02734147 High Dose Intravenous Ascorbic Acid in Severe Sepsis https://ClinicalTrials.gov/show/NCT02734147 Completed Christiana Care Health Services 2017-10-08
NCT02730624 Piperacillin/Tazobactam in Critically Ill Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02730624 Completed Prince of Songkla University 2016-05-31
NCT02721134 Diagnostic Performance of a New Bio-marker During Bacterial Sepsis https://ClinicalTrials.gov/show/NCT02721134 Recruiting Centre Hospitalier Universitaire de Nice 2018-05-31
NCT02707497 The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia https://ClinicalTrials.gov/show/NCT02707497 Recruiting Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 2021-10-31
NCT02647554 Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China https://ClinicalTrials.gov/show/NCT02647554 Recruiting Peking Union Medical College Hospital 2020-05-31
NCT02640807 A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients https://ClinicalTrials.gov/show/NCT02640807 Completed Revimmune 2018-08-27
NCT03090919 The INFUSE Trial - Intervening With Platelet Transfusions in Sepsis https://ClinicalTrials.gov/show/NCT03090919 Recruiting University of Kentucky 2020-12-31
NCT03389555 Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial https://ClinicalTrials.gov/show/NCT03389555 Recruiting Beth Israel Deaconess Medical Center 2019-12-30
NCT02503761 Bolus Versus Prolonged Infusion of Meropenem in Newborn With Late Onset Sepsis https://ClinicalTrials.gov/show/NCT02503761 Completed Mansoura University 2015-06-30
NCT02474797 Ultrasound Diaphragmatic Thickening to Monitor Its Dysfunction in Patients With Sepsis https://ClinicalTrials.gov/show/NCT02474797 Completed Groupe Hospitalier Paris Saint Joseph 2019-07-08
NCT02473263 Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock https://ClinicalTrials.gov/show/NCT02473263 Active, not recruiting Assistance Publique - Hôpitaux de Paris 2019-02-09
NCT02469571 Modulation of Gut Microbiota in Early Sepsis: A Pilot Study https://ClinicalTrials.gov/show/NCT02469571 Completed Medical University of Graz 2016-07-31
NCT02399397 Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics https://ClinicalTrials.gov/show/NCT02399397 Completed Universidade Estadual Paulista Júlio de Mesquita Filho 2015-12-31
NCT02378545 Trial of Hyperoxic O2 Therapy vs. Normoxic O2 Therapy in Sepsis https://ClinicalTrials.gov/show/NCT02378545 Completed University Hospital Plymouth NHS Trust 2016-10-31
NCT02354742 Echo vs. EGDT in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02354742 Completed Intermountain Health Care, Inc. 2017-05-31
NCT02346331 Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya https://ClinicalTrials.gov/show/NCT02346331 Completed Duke University 2016-08-31
NCT02330432 Mycobacterium w in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02330432 Recruiting Postgraduate Institute of Medical Education and Research 2019-01-31
NCT02325258 Assessment of a Proposed Microbiological Alert and Its Impact on a Sepsis Campaign https://ClinicalTrials.gov/show/NCT02325258 Completed Hospital General Universitario Gregorio Marañon 2013-01-31
NCT02295514 Correlation Between PTP1B Expression and Organ Failure During Sepsis https://ClinicalTrials.gov/show/NCT02295514 Completed University Hospital, Rouen 2016-05-31
NCT03385850 The Th17/Treg Cells and IL-23/IL-17 Axis and Early Enteral Nutrition in Sepsis https://ClinicalTrials.gov/show/NCT03385850 Completed Nanjing First Hospital, Nanjing Medical University 2018-06-30
NCT02276066 Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS https://ClinicalTrials.gov/show/NCT02276066 Active, not recruiting University of Florida 2019-11-20
NCT02273843 A Trial on Different Dosages of Vitamin D in Preterm Infants With Late-onset Sepsis https://ClinicalTrials.gov/show/NCT02273843 Completed Mansoura University Children Hospital 2015-08-31
NCT02213796 Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units https://ClinicalTrials.gov/show/NCT02213796 Completed Prince of Songkla University 2013-12-31
NCT02159079 A Randomized Controlled Trial of a Conservative Fluid Balance Strategy for Patients With Sepsis and Cardiopulmonary Dysfunction (BALANCE Study) https://ClinicalTrials.gov/show/NCT02159079 Completed Vanderbilt University Medical Center 2016-02-29
NCT02135770 Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis https://ClinicalTrials.gov/show/NCT02135770 Completed Indonesia University 2014-06-30
NCT02106975 Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury https://ClinicalTrials.gov/show/NCT02106975 Completed Virginia Commonwealth University 2017-11-16
NCT01284452 Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01284452 Completed Mahidol University 2014-12-31
NCT01275638 The Effect of Moderate-Dose Steroid Therapy in Sepsis https://ClinicalTrials.gov/show/NCT01275638 Completed TC Erciyes University 2008-05-31
NCT01988428 Prehospital Antibiotics Against Sepsis Trial https://ClinicalTrials.gov/show/NCT01988428 Completed VU University Medical Center 2017-06-30
NCT01948063 Ubiquinol (Reduced COQ10) for Patients With Sepsis https://ClinicalTrials.gov/show/NCT01948063 Completed Beth Israel Deaconess Medical Center 2014-04-30
NCT01867138 Neonatal Suspected Sepsis Treated With Cefazolin or Vancomycin https://ClinicalTrials.gov/show/NCT01867138 Completed Hospital Italiano de Buenos Aires 2010-08-31
NCT02025660 Efficacy of Mw Vaccine in Treatment of Severe Sepsis https://ClinicalTrials.gov/show/NCT02025660 Completed Postgraduate Institute of Medical Education and Research 2014-02-28
NCT03613714 Innovation in Postpartum Care for Women With Hypertensive Disorders of Pregnancy https://ClinicalTrials.gov/show/NCT03613714 Completed University of North Carolina, Chapel Hill 2019-12-31
NCT01784159 ASpirin for Patients With SEPsis and SeptIc Shock https://ClinicalTrials.gov/show/NCT01784159 Recruiting Federal University of São Paulo 2020-12-31
NCT01775020 Dose-response Study of Arginine Supplementation in Severe Sepsis https://ClinicalTrials.gov/show/NCT01775020 Completed Maastricht University Medical Center 2004-05-31
NCT01760967 Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial https://ClinicalTrials.gov/show/NCT01760967 Completed Wakayama Medical University 2016-01-31
NCT01751945 Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project https://ClinicalTrials.gov/show/NCT01751945 Completed Aga Khan University 2013-12-31
NCT01739361 Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis https://ClinicalTrials.gov/show/NCT01739361 Completed Vanderbilt University Medical Center 2013-12-31
NCT03350113 Hemospec Device for Sepsis Diagnosis https://ClinicalTrials.gov/show/NCT03350113 Completed University of Athens 2018-04-30
NCT01689441 Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis https://ClinicalTrials.gov/show/NCT01689441 Completed Brigham and Women’s Hospital 2014-02-28
NCT01649921 The Effects of Interferon-gamma on Sepsis-induced Immunoparalysis https://ClinicalTrials.gov/show/NCT01649921 Completed Radboud University 2016-12-31
NCT01626612 De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis https://ClinicalTrials.gov/show/NCT01626612 Completed Assistance Publique Hopitaux De Marseille 2013-04-30
NCT01598831 Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy https://ClinicalTrials.gov/show/NCT01598831 Completed Asahi Kasei Pharma America Corporation 2018-04-05
NCT01568853 A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis https://ClinicalTrials.gov/show/NCT01568853 Completed Jinling Hospital, China 2012-03-31
NCT03344627 Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients https://ClinicalTrials.gov/show/NCT03344627 Completed Mahidol University 2018-11-30
NCT01551394 Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days With Clinical or Confirmed Late-onset Sepsis https://ClinicalTrials.gov/show/NCT01551394 Completed PENTA Foundation 2014-12-31
NCT01525316 Lactoferrin for Prevention of Sepsis in Infants https://ClinicalTrials.gov/show/NCT01525316 Completed Universidad Peruana Cayetano Heredia 2016-10-31
NCT01484106 Cardiac Output Monitoring Managing Intravenous Therapy (COMMIT) to Treat Emergency Department Severe Sepsis https://ClinicalTrials.gov/show/NCT01484106 Completed Cheetah Medical Inc. 2014-08-31
NCT01474863 Citrulline in Severe Sepsis https://ClinicalTrials.gov/show/NCT01474863 Completed Vanderbilt University Medical Center 2016-03-31
NCT01453270 Emergency Department Management of Sepsis Patients: A Goal-Oriented Non-Invasive Sepsis Trial https://ClinicalTrials.gov/show/NCT01453270 Completed National University Hospital, Singapore 2014-03-31
NCT01450358 Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture. https://ClinicalTrials.gov/show/NCT01450358 Completed Instituto do Coracao 2016-05-31
NCT01449721 Preemptive Resuscitation for Eradication of Septic Shock https://ClinicalTrials.gov/show/NCT01449721 Completed Christiana Care Health Services 2015-01-31
NCT01434121 Ascorbic Acid (Vitamin C) Infusion in Human Sepsis https://ClinicalTrials.gov/show/NCT01434121 Completed Virginia Commonwealth University 2012-09-30
NCT01411670 Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock. https://ClinicalTrials.gov/show/NCT01411670 Completed University of Roma La Sapienza 2015-02-28
NCT01352182 Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT01352182 Completed Children’s Hospital Medical Center, Cincinnati 2016-05-31
NCT04303871 Invasive Versus Non-invasive Assessment of Blood Pressure in Hypertensive Disorders of Pregnancy https://ClinicalTrials.gov/show/NCT04303871 Completed Assiut University 2020-03-01
NCT04280497 Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis https://ClinicalTrials.gov/show/NCT04280497 Recruiting Assistance Publique - Hôpitaux de Paris 2024-10-31
NCT04227652 Control of Fever in Septic Patients https://ClinicalTrials.gov/show/NCT04227652 Completed University Hospital Ostrava 2019-02-28
NCT04216459 Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis https://ClinicalTrials.gov/show/NCT04216459 Recruiting Mansoura University 2020-07-31
NCT04160676 Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis https://ClinicalTrials.gov/show/NCT04160676 Recruiting Tanta University 2020-11-30
NCT04152980 Pentoxifylline Dose Optimization in Neonatal Sepsis https://ClinicalTrials.gov/show/NCT04152980 Recruiting Erasmus Medical Center 2020-12-31
NCT04148989 Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care https://ClinicalTrials.gov/show/NCT04148989 Enrolling by invitation Intermountain Health Care, Inc. 2021-03-31
NCT04134624 EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT04134624 Enrolling by invitation HealthPartners Institute 2021-01-31
NCT04130230 Adjuvant Use of Neostigmine in Sepsis and Septic Shock. https://ClinicalTrials.gov/show/NCT04130230 Recruiting Mansoura University 2020-03-31
NCT04111822 Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT04111822 Recruiting Institut d’Investigació Biomèdica de Girona Dr. Josep Trueta 2020-10-31
NCT04078594 Electronic Early Notification of Sepsis in Hospitalized Ward Patients https://ClinicalTrials.gov/show/NCT04078594 Recruiting King Abdullah International Medical Research Center 2021-10-30
NCT03769844 GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study https://ClinicalTrials.gov/show/NCT03769844 Recruiting Nationwide Children’s Hospital 2021-12-05
NCT03960203 Effect of a Sepsis Prediction Algorithm on Clinical Outcomes https://ClinicalTrials.gov/show/NCT03960203 Completed Dascena 2018-06-30
NCT03925857 Prevention of Sepsis-related Organ Dysfunction With Allocetra-OTS https://ClinicalTrials.gov/show/NCT03925857 Completed Enlivex Therapeutics Ltd. 2019-12-10
NCT03924518 Adjunctive Granisetron Therapy in Patients With Sepsis or Septic Shock https://ClinicalTrials.gov/show/NCT03924518 Recruiting Zhujiang Hospital 2020-12-31
NCT03869073 Evolocumab for PCSK9 Lowering in Early Acute Sepsis (The PLEASe Study) https://ClinicalTrials.gov/show/NCT03869073 Recruiting University of British Columbia 2021-02-11
NCT03865602 Improving Morbidity During Post-Acute Care Transitions for Sepsis https://ClinicalTrials.gov/show/NCT03865602 Recruiting Atrium Health 2019-12-31
NCT03829683 Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis https://ClinicalTrials.gov/show/NCT03829683 Recruiting Virginia Commonwealth University 2021-02-28
NCT03791866 The Th9/IL-9 and Early Enteral Nutrition in Sepsis https://ClinicalTrials.gov/show/NCT03791866 Recruiting Nanjing First Hospital, Nanjing Medical University 2019-12-31
NCT03755635 Neonatal Sepsis at Neonatal Intensive Care Units in Ghana https://ClinicalTrials.gov/show/NCT03755635 Recruiting University of Copenhagen 2020-01-01
NCT03754257 Effects of High-frequency Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With Sepsis https://ClinicalTrials.gov/show/NCT03754257 Recruiting Hospital Sirio-Libanes 2021-04-01
NCT03749746 Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia https://ClinicalTrials.gov/show/NCT03749746 Recruiting University of Pittsburgh 2021-12-31
NCT03730636 Procalcitonin and Duration of AntiBiotherapy In Late Onset Sepsis of Neonate https://ClinicalTrials.gov/show/NCT03730636 Recruiting Assistance Publique - Hôpitaux de Paris 2021-06-30
NCT03728790 Remote BP Monitoring in the PP Period https://ClinicalTrials.gov/show/NCT03728790 Active, not recruiting Columbia University 2019-07-28
NCT03714841 C-reactive Protein Information and Blood Cultures for Emergency Department Patients With Sepsis https://ClinicalTrials.gov/show/NCT03714841 Recruiting University of British Columbia 2019-09-15
NCT03685214 Comparison of Balanced Crystalloids and Normal Saline in Septic Patients https://ClinicalTrials.gov/show/NCT03685214 Recruiting Zhongnan Hospital 2021-04-30
NCT03655626 Implementation and Evaluations of Sepsis Watch https://ClinicalTrials.gov/show/NCT03655626 Completed Duke University 2019-07-05
NCT03592277 Vitamin C & Thiamine in Sepsis https://ClinicalTrials.gov/show/NCT03592277 Recruiting Saint Francis Care 2020-06-01
NCT03565159 Pneumococcal Vaccination to Accelerate Immune Recovery in Sepsis Survivors https://ClinicalTrials.gov/show/NCT03565159 Recruiting Guy’s and St Thomas’ NHS Foundation Trust 2021-01-31
NCT03509350 Vitamin C, Thiamine, and Steroids in Sepsis https://ClinicalTrials.gov/show/NCT03509350 Completed Emory University 2019-08-22
NCT03497182 Sepsis, Severe Sepsis and Septic Shock Detection by Breath Analysis https://ClinicalTrials.gov/show/NCT03497182 Completed Landon Pediatric Foundation 2018-10-06
NCT03472170 Clinical Trial for Valuation of the Effectiveness of Lactoferrine in the Prevention of Sepsis in New Premature Born. Bimonitorization of the Antinflammatory Mechanisms, Antioxidants and the Intestinal Microbiote. https://ClinicalTrials.gov/show/NCT03472170 Recruiting Maimónides Biomedical Research Institute of Córdoba 2020-03-01
NCT03454087 Study of Early Enteral Dextrose in Sepsis https://ClinicalTrials.gov/show/NCT03454087 Completed University of Pittsburgh 2020-03-02
NCT03453177 Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsis https://ClinicalTrials.gov/show/NCT03453177 Completed Drugs for Neglected Diseases 2019-03-14
NCT03452865 Esomeprazole to Reduce Organ Failure in Sepsis https://ClinicalTrials.gov/show/NCT03452865 Recruiting Università Vita-Salute San Raffaele 2022-03-31
NCT03422159 Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis. https://ClinicalTrials.gov/show/NCT03422159 Completed Community Medical Center, Toms River, NJ 2019-06-05
NCT01264536 Pilot Study: Lactoferrin for Prevention of Neonatal Sepsis https://ClinicalTrials.gov/show/NCT01264536 Completed Universidad Peruana Cayetano Heredia 2011-10-31
NCT01247792 End-of-life Decision-making in Patients With Sepsis-related Organ Failure https://ClinicalTrials.gov/show/NCT01247792 Completed Center for Sepsis Control and Care, Germany 2014-09-30
NCT01223690 Clarithromycin as Immunomodulator for the Management of Sepsis https://ClinicalTrials.gov/show/NCT01223690 Completed University of Athens 2010-11-30
NCT01187134 Medical Education for Sepsis Source Control and Antibiotics https://ClinicalTrials.gov/show/NCT01187134 Completed Center for Sepsis Control and Care, Germany 2013-06-30
NCT01145560 A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFabâ„¢) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock https://ClinicalTrials.gov/show/NCT01145560 Completed AstraZeneca 2012-05-31
NCT01144624 A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFabâ„¢) in Japanese With Severe Sepsis/Septic Shock https://ClinicalTrials.gov/show/NCT01144624 Completed AstraZeneca 2011-08-31
NCT01139489 Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU’s) https://ClinicalTrials.gov/show/NCT01139489 Completed VU University Medical Center 2014-08-31
NCT01089361 Immunomodulatory Properties of Ketamine in Sepsis https://ClinicalTrials.gov/show/NCT01089361 Completed Beth Israel Deaconess Medical Center 2010-06-30
NCT01069146 Mild Therapeutic Hypothermia During Severe Sepsis https://ClinicalTrials.gov/show/NCT01069146 Completed University Hospital, Brest 2005-01-31
NCT01027897 Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients https://ClinicalTrials.gov/show/NCT01027897 Completed Emory University 2011-12-31
NCT01027429 Simplified Antibiotic Therapy for Sepsis in Young Infants https://ClinicalTrials.gov/show/NCT01027429 Completed Aga Khan University 2013-12-31
NCT01013662 Lipid Profile in Patients With Severe Sepsis or Septic Shock Under Strict or Liberal Glycemic Control https://ClinicalTrials.gov/show/NCT01013662 Completed University of Sao Paulo 2007-07-31
NCT00994812 The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS) https://ClinicalTrials.gov/show/NCT00994812 Completed University of Oulu 2009-12-31
NCT00962156 Scandinavian Starch for Severe Sepsis/Septic Shock Trial https://ClinicalTrials.gov/show/NCT00962156 Completed Scandinavian Critical Care Trials Group 2012-03-31
NCT00926497 Procalcitonin-Guided Decision Making to Shorten Antibiotic Therapy in Suspected Neonatal Early-Onset Sepsis https://ClinicalTrials.gov/show/NCT00926497 Completed Luzerner Kantonsspital 2006-12-31
NCT00844337 Simplified Antibiotic Regimens for Outpatient Treatment of Suspected Sepsis in Neonates and Young Infants in Bangladesh https://ClinicalTrials.gov/show/NCT00844337 Completed Johns Hopkins Bloomberg School of Public Health 2013-09-30
NCT04203524 Procalcitonin and Antimicrobial Utilization in Critically Ill Cancer Patients With Sepsis https://ClinicalTrials.gov/show/NCT04203524 Recruiting King Hussein Cancer Center 2021-08-21
NCT03334227 High Flow Nasal Cannula in Severe Sepsis https://ClinicalTrials.gov/show/NCT03334227 Recruiting Althaia Xarxa Assistencial Universitària de Manresa 2020-02-28
NCT00832039 Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis https://ClinicalTrials.gov/show/NCT00832039 Completed Kompetenznetz Sepsis 2013-03-31
NCT03920982 Prognostic Value Serum Concentration of Indoxyl Sulfate During Acute Kidney Injury in Septic Shock Patients. https://ClinicalTrials.gov/show/NCT03920982 Recruiting Centre Hospitalier Universitaire, Amiens 2022-04-30
NCT02654561 Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation https://ClinicalTrials.gov/show/NCT02654561 Recruiting China Medical University, China 2021-02-28
NCT01538875 Hydralazine Versus Labetalol for the Management of Hypertensive Disorders of Pregnancy https://ClinicalTrials.gov/show/NCT01538875 Completed Saint Thomas Hospital, Panama 2013-04-30
NCT03306186 Hemospec Device for the Diagnosis of Sepsis https://ClinicalTrials.gov/show/NCT03306186 Completed University of Athens 2017-12-30
NCT02468310 Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana https://ClinicalTrials.gov/show/NCT02468310 Completed Julius Global Health 2017-02-09
NCT01333982 Neonatal Sepsis, Evaluation, Bangladesh https://ClinicalTrials.gov/show/NCT01333982 Completed International Centre for Diarrhoeal Disease Research, Bangladesh 2013-12-31
NCT03764085 Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis. https://ClinicalTrials.gov/show/NCT03764085 Completed Yuria-Pharm 2019-12-11
NCT03728998 Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis https://ClinicalTrials.gov/show/NCT03728998 Completed Medical Centre Leeuwarden 2019-03-23
NCT00772096 Septic Encephalopathy and Late Cognitive Dysfunction https://ClinicalTrials.gov/show/NCT00772096 Completed University Hospital, Basel, Switzerland 2011-06-30
NCT00732277 Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study https://ClinicalTrials.gov/show/NCT00732277 Completed University Hospital Southampton NHS Foundation Trust 2012-04-30
NCT00711620 Efficacy of Thymosin alpha1 for Severe Sepsis https://ClinicalTrials.gov/show/NCT00711620 Completed Sun Yat-sen University 2010-12-31
NCT00707122 Volume Replacement With Albumin in Severe Sepsis https://ClinicalTrials.gov/show/NCT00707122 Completed Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico 2013-04-30
NCT00707785 Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis https://ClinicalTrials.gov/show/NCT00707785 Completed Johns Hopkins University 2011-04-30
NCT00646399 Safety and Efficacy of Pagibaximab Injection in Very Low Birth Weight Neonates for Prevention of Staphylococcal Sepsis https://ClinicalTrials.gov/show/NCT00646399 Completed Biosynexus Incorporated 2011-05-31
NCT00634075 Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00634075 Completed Li Shin Hospital 2009-08-31
NCT00630656 Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis https://ClinicalTrials.gov/show/NCT00630656 Completed Agennix 2009-08-31
NCT00608322 Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis https://ClinicalTrials.gov/show/NCT00608322 Completed National Institute of General Medical Sciences (NIGMS) 2013-04-30
NCT00568893 An Open Label Study of Severe Sepsis in Adults https://ClinicalTrials.gov/show/NCT00568893 Completed Eli Lilly and Company NA
NCT00568737 The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death https://ClinicalTrials.gov/show/NCT00568737 Completed Eli Lilly and Company NA
NCT00559130 Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis https://ClinicalTrials.gov/show/NCT00559130 Completed MedaSorb Technologies, Inc 2011-04-30
NCT00537693 Cytokine Removal by CRRT in Pediatric Sepsis https://ClinicalTrials.gov/show/NCT00537693 Completed Sunnybrook Health Sciences Centre 2010-04-30
NCT00534287 Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00534287 Completed Kompetenznetz Sepsis 2010-04-30
NCT00510835 Protocolized Care for Early Septic Shock https://ClinicalTrials.gov/show/NCT00510835 Completed University of Pittsburgh 2013-07-31
NCT00487656 Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation https://ClinicalTrials.gov/show/NCT00487656 Completed Artisan Pharma, Inc. 2010-05-31
NCT00799916 Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis https://ClinicalTrials.gov/show/NCT00799916 Completed Universidad Nacional de La Plata 2009-08-31
NCT00464204 Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00464204 Completed Fresenius Kabi 2010-05-31
NCT00430859 Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis https://ClinicalTrials.gov/show/NCT00430859 Completed AM-Pharma 2006-03-31
NCT00406198 Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis https://ClinicalTrials.gov/show/NCT00406198 Completed Hopital Lariboisière NA
NCT00386425 Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated) https://ClinicalTrials.gov/show/NCT00386425 Completed Eli Lilly and Company 2009-08-31
NCT00372502 Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation https://ClinicalTrials.gov/show/NCT00372502 Completed National Institute of General Medical Sciences (NIGMS) 2008-12-31
NCT00346580 The Effects of HIV Protease Inhibitors in Severe Sepsis https://ClinicalTrials.gov/show/NCT00346580 Completed Mayo Clinic 2005-09-30
NCT00334828 ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00334828 Completed Eisai Inc. 2011-01-31
NCT00333593 Super High-Flux - High Volume Dialysis in Sepsis-Induced Acute Renal Failure https://ClinicalTrials.gov/show/NCT00333593 Completed Austin Health NA
NCT00329680 The Effects of Eicosapentaenoic Acid (EPA), Gamma-Linolenic Acid (GLA) and Antioxidants in the Treatment of Sepsis https://ClinicalTrials.gov/show/NCT00329680 Completed Fernandes Tavora Hospital 2008-12-31
NCT00318552 Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients. https://ClinicalTrials.gov/show/NCT00318552 Completed Pfizer 2006-06-30
NCT03788772 Systems Analysis of Antigen Presenting Cells in Human Sepsis https://ClinicalTrials.gov/show/NCT03788772 Recruiting Assistance Publique - Hôpitaux de Paris 2022-07-15
NCT00273728 BaSES Trial: Basel Starch Evaluation in Sepsis https://ClinicalTrials.gov/show/NCT00273728 Completed University Hospital, Basel, Switzerland 2010-06-30
NCT00252915 Reconstruction of Monocytic Immunocompetence by Granulocyte-macrophage-colony Stimulating Factor (GM-CSF) in Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00252915 Completed Charite University, Berlin, Germany 2007-01-31
NCT00222222 Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis https://ClinicalTrials.gov/show/NCT00222222 Completed Universitätsmedizin Mannheim 2011-12-31
NCT00159952 Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00159952 Completed Policlinico Hospital 2007-03-31
NCT00143611 Efficacy & Safety of Resatorvid in Adults With Severe Sepsis https://ClinicalTrials.gov/show/NCT00143611 Completed Takeda 2007-02-28
NCT00142220 The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients https://ClinicalTrials.gov/show/NCT00142220 Completed University Medicine Greifswald NA
NCT00138112 Trial of Prophylactic Versus Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation https://ClinicalTrials.gov/show/NCT00138112 Completed Memorial Sloan Kettering Cancer Center NA
NCT00135473 Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial) https://ClinicalTrials.gov/show/NCT00135473 Completed SepNet - Critical Care Trials Group NA
NCT00113191 Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants https://ClinicalTrials.gov/show/NCT00113191 Completed Bristol-Myers Squibb 2006-06-30
NCT00100308 Unfractioned Heparin for Treatment of Sepsis https://ClinicalTrials.gov/show/NCT00100308 Completed Universidad de Antioquia 2007-07-31
NCT00049777 A Trial of Heparin in Patients With Severe Sepsis Who Are Undergoing Treatment With Drotrecogin Alfa (Activated) https://ClinicalTrials.gov/show/NCT00049777 Completed Eli Lilly and Company NA
NCT00049764 Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis https://ClinicalTrials.gov/show/NCT00049764 Completed Eli Lilly and Company NA
NCT00046072 A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00046072 Completed Eisai Inc. NA
NCT00042588 A Safety and Efficacy Study of Hospitalized Patients With Community-Acquired Pneumonia and Sepsis https://ClinicalTrials.gov/show/NCT00042588 Completed ICOS Corporation NA
NCT00034476 A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00034476 Completed Eli Lilly and Company NA
NCT00031512 Pleconaril Enteroviral Sepsis Syndrome https://ClinicalTrials.gov/show/NCT00031512 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2010-09-30
NCT00819416 Fluid Resuscitation in Early Septic Shock https://ClinicalTrials.gov/show/NCT00819416 Completed Ottawa Hospital Research Institute 2009-10-31
NCT00000543 Oral Calcium in Pregnant Women With Hypertension https://ClinicalTrials.gov/show/NCT00000543 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00089986 GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults https://ClinicalTrials.gov/show/NCT00089986 Completed GlaxoSmithKline 2007-04-01
NCT00000534 Calcium for Pre-Eclampsia Prevention (CPEP) https://ClinicalTrials.gov/show/NCT00000534 Completed Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03356249 Next-Generation Sequencing Diagnostics of Bacteremia in Sepsis https://ClinicalTrials.gov/show/NCT03356249 Recruiting University Hospital Heidelberg 2020-12-31
NCT04130789 Personalized Swiss Sepsis Study https://ClinicalTrials.gov/show/NCT04130789 Recruiting University Hospital, Basel, Switzerland 2022-06-30
NCT03408600 Physiologic Indicators for Prognosis in Abdominal Sepsis Study https://ClinicalTrials.gov/show/NCT03408600 Completed World Society of Emergency Surgery 2018-05-01
NCT03378258 Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA. https://ClinicalTrials.gov/show/NCT03378258 Completed Belfast Health and Social Care Trust 2019-06-30
NCT01319630 The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients https://ClinicalTrials.gov/show/NCT01319630 Completed Mercy Research 2013-12-31
NCT03870789 Field Paramedic Application of Sepsis Triage https://ClinicalTrials.gov/show/NCT03870789 Recruiting Hamilton Health Sciences Corporation 2019-05-01
NCT03355833 Comparing Prognostic Performance of SEPSIS 2 and SEPSIS 3 Strategies at the Emergency Service https://ClinicalTrials.gov/show/NCT03355833 Completed Centre Hospitalier Régional Metz-Thionville 2016-08-31
NCT03314831 The Role of Myristic Acid in Serum for Early Diagnosis of Sepsis and Comparison With Selected Biomarkers of Sepsis https://ClinicalTrials.gov/show/NCT03314831 Recruiting Charles University, Czech Republic 2019-12-31
NCT03310840 A Study On the Risk of Nosocomial Infection in Mechanically Ventilated Neonate In NICU of Assiut University Children Hospital (Nicu Eta) https://ClinicalTrials.gov/show/NCT03310840 Completed Assiut University 2019-03-30
NCT03280576 Validation of Progranulin as a Biomarker for Sepsis https://ClinicalTrials.gov/show/NCT03280576 Completed Ludwig-Maximilians - University of Munich 2019-04-30
NCT03249597 Predict Sepsis; the Predictive Value of Bedside Measures in the Ambulance https://ClinicalTrials.gov/show/NCT03249597 Recruiting Karolinska Institutet 2018-10-31
NCT03249246 Epidemiology of Sepsis in Turkish ICUs. https://ClinicalTrials.gov/show/NCT03249246 Completed Turkish Intensive Care Society 2016-01-28
NCT03244293 Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis https://ClinicalTrials.gov/show/NCT03244293 Recruiting Suez Canal University 2021-01-01
NCT03231956 CLEAR Sepsis Clinical Study https://ClinicalTrials.gov/show/NCT03231956 Recruiting Edwards Lifesciences 2021-12-31
NCT03226366 Effect of Emergency Department Care Reorganization on Door-to-antibiotic Times for Sepsis (LDS SWARM) https://ClinicalTrials.gov/show/NCT03226366 Completed Intermountain Health Care, Inc. 2017-01-31
NCT03145428 Evaluation of Monocyte Volume Distribution Width (MDW) for Early Detection of Sepsis https://ClinicalTrials.gov/show/NCT03145428 Completed Beckman Coulter, Inc. 2017-12-22
NCT03141112 The Benefits of Early Initiation of Continual Renal Replacement Therapy in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT03141112 Enrolling by invitation University Hospital Olomouc 2018-12-31
NCT03133208 Sepsis Associated Encephalopathy (SAE) Biomarkers https://ClinicalTrials.gov/show/NCT03133208 Recruiting University of Florida 2021-04-18
NCT03113721 Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis https://ClinicalTrials.gov/show/NCT03113721 Active, not recruiting Axis Shield Diagnostics Ltd 2018-12-31
NCT03077672 Mitochondrial DNA as a Biomarker of Sepsis Severity https://ClinicalTrials.gov/show/NCT03077672 Recruiting Weill Medical College of Cornell University 2021-12-31
NCT03076619 A Clinical Study of Fundus Findings in Toxaemia of Pregnancy https://ClinicalTrials.gov/show/NCT03076619 Completed B. J. Medical College, Ahmedabad 2006-06-30
NCT03037281 Release of Nociceptin From Granulocytes in Sepsis https://ClinicalTrials.gov/show/NCT03037281 Completed University of Leicester 2019-06-30
NCT03015584 Systems Biology Approach to Cognitive Impairment After SepsiS https://ClinicalTrials.gov/show/NCT03015584 Completed Intermountain Health Care, Inc. 2017-07-31
NCT03010410 Platelet Immune Responses in Aging and Influenza and Sepsis (INVACS) https://ClinicalTrials.gov/show/NCT03010410 Enrolling by invitation Intermountain Health Care, Inc. 2019-10-31
NCT02988414 Diagnosis of Bacteremia/Septicemia and Culture Negative Endocarditis by the Karius Sequencing-Based Infectious Disease Diagnostic Assay https://ClinicalTrials.gov/show/NCT02988414 Completed Karius, Inc. 2017-04-30
NCT02971111 Thromboelastometry in Assessment of Sepsis Coagulopathy https://ClinicalTrials.gov/show/NCT02971111 Completed University Hospital, Motol 2016-10-31
NCT02953002 The Correlation Between The New Sepsis Scores - SOFA, Quick SOFA and Calibrated Automated Thrombogram Values https://ClinicalTrials.gov/show/NCT02953002 Recruiting HaEmek Medical Center, Israel 2019-12-31
NCT02934997 The Role of Dysfunctional HDL in Sepsis https://ClinicalTrials.gov/show/NCT02934997 Completed University of Florida 2019-05-03
NCT02887274 Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe Sepsis https://ClinicalTrials.gov/show/NCT02887274 Recruiting Chang Gung Memorial Hospital 2018-12-31
NCT02739152 TRIAGE: TRIage of Sepsis At emerGency dEpartment https://ClinicalTrials.gov/show/NCT02739152 Completed BioMérieux 2018-01-31
NCT02738164 SEPSIS 3 Critera for Risk Stratification in Emergency Patients https://ClinicalTrials.gov/show/NCT02738164 Completed Societe Française de Medecine d’urgence 2016-07-31
NCT02730468 SEP-SEQ Trial - Determining the Etiology of Sepsis Using an Infectious Disease Diagnostic Sequencing Assay https://ClinicalTrials.gov/show/NCT02730468 Completed Karius, Inc. 2017-09-30
NCT02728401 Genotypes and Phenotypes in Pediatric SIRS and Sepsis https://ClinicalTrials.gov/show/NCT02728401 Completed Seattle Children’s Hospital 2017-12-31
NCT02707718 Biomarkers for the Early Identification of Sepsis in the Emergency Department https://ClinicalTrials.gov/show/NCT02707718 Completed Pitié-Salpêtrière Hospital 2018-03-03
NCT02589431 Comparison of Total, Salivary and Calculated Free Cortisol Levels in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02589431 Completed TC Erciyes University 2011-06-30
NCT02569086 Piperacillin PK Analysis in Severe Sepsis Patients https://ClinicalTrials.gov/show/NCT02569086 Completed University of Aarhus 2016-06-30
NCT02562261 Platelet REactivity in Sepsis Syndrome (PRESS) https://ClinicalTrials.gov/show/NCT02562261 Completed University Hospital of Patras 2016-06-30
NCT02544490 Defining Circulating Micro-RNA Biomarkers for the Early Diagnosis and Prognosis of Sepsis https://ClinicalTrials.gov/show/NCT02544490 Completed National University Hospital, Singapore 2018-12-31
NCT02533011 Evaluation of the Heparin Binding Protein Levels in Sepsis https://ClinicalTrials.gov/show/NCT02533011 Completed Christiana Care Health Services 2016-12-31
NCT02532959 Diagnostic Breath Analysis Study to Detect Sepsis https://ClinicalTrials.gov/show/NCT02532959 Completed Landon Pediatric Foundation 2015-09-30
NCT02539147 Characterization of Non-canonical Way in Inflammasome Monocytes of Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02539147 Completed Groupe Hospitalier Paris Saint Joseph 2014-12-31
NCT02486783 Infection, Sepsis and Meningitis in Surinamese Neonates https://ClinicalTrials.gov/show/NCT02486783 Completed Academic Hospital Paramaribo 2016-08-31
NCT02444871 IgM-enriched Immunoglobulin Attenuates Systemic Endotoxin Activity in Early Severe Sepsis https://ClinicalTrials.gov/show/NCT02444871 Completed Goethe University 2013-07-31
NCT02448472 Epidemiology of Sepsis in China https://ClinicalTrials.gov/show/NCT02448472 Completed Southeast University, China 2015-12-31
NCT02430142 Microcirculatory Oxygen Uptake in Sepsis https://ClinicalTrials.gov/show/NCT02430142 Completed Universitätsmedizin Mannheim 2016-10-31
NCT02410486 Early-Onset Sepsis an NICHD/CDC Surveillance Study https://ClinicalTrials.gov/show/NCT02410486 Completed NICHD Neonatal Research Network 2017-12-31
NCT02393781 Adrenomedullin and Outcome in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02393781 Completed Sphingotec GmbH 2016-05-31
NCT02370186 The Role of Dysfunctional HDL in Severe Sepsis https://ClinicalTrials.gov/show/NCT02370186 Completed University of Florida 2017-03-12
NCT02353910 VTE Incidence in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02353910 Completed University of Utah 2014-12-31
NCT02288715 Relationship of Cerebral Perfusion Pressure Variability to Sepsis-associated Encephalopathy https://ClinicalTrials.gov/show/NCT02288715 Completed West China Hospital 2015-03-31
NCT02281890 Neurodevelopmental Outcomes After Suspected or Proven Sepsis: Secondary Analysis of INIS Trial Database https://ClinicalTrials.gov/show/NCT02281890 Completed University of Edinburgh 2007-09-30
NCT02217592 Causes and Factors Associated With Outcomes in Community-acquired Sepsis and Severe Sepsis in Northeast Thailand https://ClinicalTrials.gov/show/NCT02217592 Completed University of Oxford 2017-02-28
NCT02188992 Early PREdiction of Severe Sepsis I (ExPRES-Sepsis I) Study https://ClinicalTrials.gov/show/NCT02188992 Completed University of Edinburgh 2016-01-31
NCT02157259 An Observational Study of the Causes, Management, and Outcomes of Community-acquired Sepsis and Severe Sepsis in Southeast Asia https://ClinicalTrials.gov/show/NCT02157259 Completed University of Oxford 2016-02-29
NCT02026856 Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT02026856 Completed Pavol Jozef Safarik University 2013-12-31
NCT01995448 Prognostic Interest of Leucocyte Immunophenotyping During the Acute Phase of Sepsis https://ClinicalTrials.gov/show/NCT01995448 Completed University Hospital, Limoges 2015-06-30
NCT01968746 The AVERT Sepsis Investigation https://ClinicalTrials.gov/show/NCT01968746 Completed Christiana Care Health Services 2015-01-31
NCT01964690 Lactate Use as Triage Tool in Sepsis : Veinous, Capillary or Arterial? https://ClinicalTrials.gov/show/NCT01964690 Completed Hopital Saint Roch 2014-04-30
NCT01943747 International Multicentre Prevalence Study on Sepsis https://ClinicalTrials.gov/show/NCT01943747 Completed European Society of Intensive Care Medicine 2013-11-30
NCT01929772 German Lactat Clearance in Severe Sepsis https://ClinicalTrials.gov/show/NCT01929772 Completed RWTH Aachen University 2015-04-30
NCT01919138 Outcomes of Severe Sepsis Patients in Surgical Intensive Care Units https://ClinicalTrials.gov/show/NCT01919138 Completed National Taiwan University Hospital 2013-12-31
NCT01867905 Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT01867905 Completed University of British Columbia 2018-09-05
NCT02025699 Prospective Study to Characterize Host-pathogen Related Factors in Hospitalized and ED Patients With LRTI and/or Sepsis https://ClinicalTrials.gov/show/NCT02025699 Completed MeMed Diagnostics Ltd. 2016-06-30
NCT01847248 HSPA12B as a Potential Biomarker for Sepsis and Severe Sepsis https://ClinicalTrials.gov/show/NCT01847248 Completed Changhai Hospital 2013-03-31
NCT01725061 Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis https://ClinicalTrials.gov/show/NCT01725061 Completed Emory University 2012-09-30
NCT01670383 Repository for Sepsis and Postresuscitation Samples https://ClinicalTrials.gov/show/NCT01670383 Recruiting Seoul National University Hospital 2020-12-31
NCT01649440 Sepsis Metabolomics https://ClinicalTrials.gov/show/NCT01649440 Completed Chinese PLA General Hospital 2012-03-31
NCT01578226 Procalcitonin in Cirrhotic Patients at High Risk for Sepsis https://ClinicalTrials.gov/show/NCT01578226 Completed University of Modena and Reggio Emilia 2010-09-30
NCT00806325 Clinical Factors Associated With the Development of Severe Sepsis in Patients Being Treated for Acute Myeloid Leukemia https://ClinicalTrials.gov/show/NCT00806325 Completed Ohio State University 2010-02-28
NCT01530932 Immune Activation, Hypoxia and Vasoreaction in Sepsis of Pulmonary Versus Abdominal Origin https://ClinicalTrials.gov/show/NCT01530932 Completed Universitätsmedizin Mannheim 2014-04-30
NCT01530854 Plasma Free Fatty Acids in Risk Assessment of Sepsis in the Emergency Department: A Prospective Pilot Study https://ClinicalTrials.gov/show/NCT01530854 Completed The Cleveland Clinic 2012-01-31
NCT01523717 Procalcitonin Monitoring Sepsis Study https://ClinicalTrials.gov/show/NCT01523717 Completed Brahms AG 2014-03-31
NCT01431326 Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care https://ClinicalTrials.gov/show/NCT01431326 Completed Duke University 2019-11-30
NCT01426711 Critical Care Excellence in Sepsis and Trauma https://ClinicalTrials.gov/show/NCT01426711 Completed Medical University of South Carolina 2012-03-31
NCT01410578 The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO https://ClinicalTrials.gov/show/NCT01410578 Completed Chinese PLA General Hospital 2011-03-31
NCT01403935 Sepsis Institutional Registry in Hospital Italiano de Buenos Aires https://ClinicalTrials.gov/show/NCT01403935 Completed Hospital Italiano de Buenos Aires 2014-03-31
NCT01388725 Comparison the Value of Several Biomarkers of Sepsis https://ClinicalTrials.gov/show/NCT01388725 Completed Chinese PLA General Hospital 2011-07-31
NCT01378169 SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICU https://ClinicalTrials.gov/show/NCT01378169 Completed Groupe Hospitalier Paris Saint Joseph 2013-01-01
NCT01362829 Outcome Predictors in Patients With Severe Sepsis and Optimized Central Venous Oxygen Saturation https://ClinicalTrials.gov/show/NCT01362829 Completed National Taiwan University Hospital 2011-05-31
NCT01333657 The Application of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis & Relevant Acute Kidney Injuries https://ClinicalTrials.gov/show/NCT01333657 Completed Chinese PLA General Hospital 2011-04-30
NCT01332734 Microcirculatory Changes During Magnesium Sulphate Infusion in Sepsis https://ClinicalTrials.gov/show/NCT01332734 Completed Medical Centre Leeuwarden 2010-08-31
NCT01328509 Zinc and Inflammation in Sepsis https://ClinicalTrials.gov/show/NCT01328509 Completed University of Aberdeen 2013-05-31
NCT03412552 Risk Analysis of Intensive Care Mangement on Maternal and Fetal Outcome of Severe Preeclampsia and Eclampsia https://ClinicalTrials.gov/show/NCT03412552 Completed Cairo University 2017-10-01
NCT03620409 Identification of Cardiovascular and Molecular Prognostic Factors for the Mid- and Long-term Outcome of Sepsis https://ClinicalTrials.gov/show/NCT03620409 Recruiting Jena University Hospital 2020-12-31
NCT04353388 Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Washington University https://ClinicalTrials.gov/show/NCT04353388 Recruiting Beckman Coulter, Inc. 2020-05-31
NCT04322942 Sepsis Prediction by Monocyte Distribution Width and Procalcitonin https://ClinicalTrials.gov/show/NCT04322942 Recruiting Chang Gung Memorial Hospital 2020-09-30
NCT04291417 Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Baylor S&W https://ClinicalTrials.gov/show/NCT04291417 Recruiting Beckman Coulter, Inc. 2020-04-30
NCT04289506 Validation of Molecular and Protein Biomarkers in Sepsis https://ClinicalTrials.gov/show/NCT04289506 Recruiting Public Health England 2021-11-30
NCT04214743 Ocular Microvascular Changes in Patients With Sepsis https://ClinicalTrials.gov/show/NCT04214743 Completed Lithuanian University of Health Sciences 2019-08-31
NCT04199962 Genomics in Infection and Sepsis to Predict Organ Dysfunction and Outcomes in Sepsis https://ClinicalTrials.gov/show/NCT04199962 Recruiting Chinese University of Hong Kong 2022-11-11
NCT04157452 Prediction of Sepsis After Flexible Ureteroscopy https://ClinicalTrials.gov/show/NCT04157452 Completed Tongji Hospital 2019-08-01
NCT04149132 Pulse Photoplethysmography as an Early Tool for the Diagnosis of Sepsis https://ClinicalTrials.gov/show/NCT04149132 Active, not recruiting Hellenic Institute for the Study of Sepsis 2020-05-08
NCT04141410 Global Longitudinal Strain Assessment in Cardiogenic Shock During Sepsis https://ClinicalTrials.gov/show/NCT04141410 Recruiting Azienda USL Toscana Centro 2020-10-21
NCT04126629 Association of Hypertensive Disorder of Pregnancy With Sleep-disordered Breathing. https://ClinicalTrials.gov/show/NCT04126629 Recruiting The Cooper Health System 2020-09-01
NCT04118179 New Strategy to Predict Early Sepsis https://ClinicalTrials.gov/show/NCT04118179 Recruiting University of British Columbia 2020-07-31
NCT04117568 The Role of Emergency Neutrophils and Glycans in Postoperative and Septic Patients https://ClinicalTrials.gov/show/NCT04117568 Recruiting Göteborg University 2020-12-31
NCT04114214 Objective Sepsis Identification Tool to Study Sepsis Epidemiology https://ClinicalTrials.gov/show/NCT04114214 Completed Chinese University of Hong Kong 2019-10-10
NCT04105699 Evaluation of Immunoassay Measurements of Pancreatic Stone Protein Performed on abioSCOPE® Device With the PSP Assay on ICU Patients at Risk of Sepsis as an Aid in Identifying Sepsis https://ClinicalTrials.gov/show/NCT04105699 Recruiting Abionic SA 2020-07-31
NCT04094818 HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis https://ClinicalTrials.gov/show/NCT04094818 Enrolling by invitation Inflammatix 2021-10-31
NCT04068298 Temperature Gradients for Sepsis Severity and Fluid Resuscitation https://ClinicalTrials.gov/show/NCT04068298 Recruiting Nanfang Hospital of Southern Medical University 2022-09-01
NCT04063332 Functionality of Endogenous Biological Clock in Sepsis https://ClinicalTrials.gov/show/NCT04063332 Recruiting University of Athens 2020-06-30
NCT04055727 Sepsis at Södersjukhuset-Adherence to Treatment Guidelines https://ClinicalTrials.gov/show/NCT04055727 Recruiting Karolinska Institutet 2021-12-01
NCT04033653 Long-term Quality of Life Among Survivors of Sepsis in China Assessed by EQ-5D https://ClinicalTrials.gov/show/NCT04033653 Completed Southeast University, China 2018-08-31
NCT04032743 Risk Factors and Treatment Outcome of Oncology Children Hospitalized in the Intensive Care Unit Due to Sepsis https://ClinicalTrials.gov/show/NCT04032743 Active, not recruiting Rabin Medical Center 2020-07-31
NCT04028102 Ultrasound Optimization of Initial Fluid Challenge in Sepsis https://ClinicalTrials.gov/show/NCT04028102 Recruiting Nantes University Hospital 2020-03-01
NCT03996759 Early Prediction of Sepsis by Using Metabolomics https://ClinicalTrials.gov/show/NCT03996759 Recruiting Southwest Hospital, China 2021-06-18
NCT03960307 Glycocalyx and Microcirculation in Sepsis https://ClinicalTrials.gov/show/NCT03960307 Completed University Hospital Muenster 2017-09-30
NCT03952390 Effect of Renin-Angiotensin System on Platelet in Patient With Sepsis https://ClinicalTrials.gov/show/NCT03952390 Completed Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 2019-12-10
NCT03938220 Electrical Cardiometry Compared to Transthoracic Echocardiography in Fluid Responsiveness in Sepsis https://ClinicalTrials.gov/show/NCT03938220 Recruiting Tanta University 2020-04-01
NCT03932123 Antibiotic Therapy for Early Onset Neonatal Sepsis https://ClinicalTrials.gov/show/NCT03932123 Recruiting Shandong University 2025-10-31
NCT03884894 Neonatal Sepsis Diagnosis: ; PCR Commercial Technique and Blood Culture https://ClinicalTrials.gov/show/NCT03884894 Completed IRCCS Policlinico S. Matteo 2016-01-31
NCT03884595 Early Identification of Sepsis in Children https://ClinicalTrials.gov/show/NCT03884595 Recruiting Brno University Hospital 2021-12-31
NCT03881566 Presepsin as Detective Marker of Sepsis in Immunodeficiency ICU Patients https://ClinicalTrials.gov/show/NCT03881566 Recruiting Seoul St. Mary’s Hospital 2020-12-31
NCT03803813 Incidence of Sepsis After Craniocerebral Operation https://ClinicalTrials.gov/show/NCT03803813 Active, not recruiting Beijing Tiantan Hospital 2018-12-31
NCT03802136 Multiple Biomarkers in ICU Sepsis Patients https://ClinicalTrials.gov/show/NCT03802136 Recruiting Zhongnan Hospital 2019-06-30
NCT03799159 Renal Arterial Resistive Index Versus Novel Biomarkers for Early Prediction of Sepsis Associated-acute Kidney Injury https://ClinicalTrials.gov/show/NCT03799159 Recruiting Alexandria University 2020-06-30
NCT03796715 Red Cell Distribution Width Versus Presepsin (Soluble CD14) as a Prognostic Marker in Critically-ill Sepsis Patients https://ClinicalTrials.gov/show/NCT03796715 Completed Ain Shams University 2018-11-20
NCT03782454 Quantification of Bacterial DNA in Sepsis https://ClinicalTrials.gov/show/NCT03782454 Recruiting Region Örebro County 2021-12-31
NCT03777670 nSeP: Detecting Neonatal Sepsis by Immune-Metabolic Network Analysis https://ClinicalTrials.gov/show/NCT03777670 Recruiting Cardiff and Vale University Health Board 2023-02-28
NCT03744741 HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study https://ClinicalTrials.gov/show/NCT03744741 Completed Inflammatix 2019-11-25
NCT03721302 NeoAMR Observational Study in Neonatal Sepsis https://ClinicalTrials.gov/show/NCT03721302 Recruiting Drugs for Neglected Diseases 2019-12-31
NCT03708796 DIAGNOSis of Infection in Emergency Department https://ClinicalTrials.gov/show/NCT03708796 Completed Association pour la Formation l’Enseignement et la Recherche du Service de l’Accueil des Urgences 2018-04-13
NCT03682003 Hepcidin: a Prognostic Marker of Morbidity and Mortality in Severe Sepsis? https://ClinicalTrials.gov/show/NCT03682003 Active, not recruiting Rennes University Hospital 2017-07-12
NCT03661450 Evaluation of CDSS in Detection of SIRS and Sepsis in Pediatric Patients https://ClinicalTrials.gov/show/NCT03661450 Completed Hannover Medical School 2019-03-31
NCT03654456 Impact of Sleep Apnea on Sepsis Mortality https://ClinicalTrials.gov/show/NCT03654456 Recruiting Taipei Veterans General Hospital, Taiwan 2019-05-27
NCT03641534 Monitoring of Perfusion in Sepsis and Malaria https://ClinicalTrials.gov/show/NCT03641534 Recruiting University of Oxford 2019-09-30
NCT03623503 Clinical Criteria for a Pathogen in Term Newborn Suspected of Neonatal Sepsis https://ClinicalTrials.gov/show/NCT03623503 Completed Centre Hospitalier Universitaire, Amiens 2017-07-12
NCT02276417 PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors https://ClinicalTrials.gov/show/NCT02276417 Recruiting University of Florida 2020-07-31
NCT03598127 Vitamin A Status in Critically Ill Children With Sepsis and Its Association With Illness Severity https://ClinicalTrials.gov/show/NCT03598127 Recruiting West China Hospital 2020-04-01
NCT03588325 Evaluation of MDW for Early Detection of Sepsis, Clinical Validity https://ClinicalTrials.gov/show/NCT03588325 Completed Beckman Coulter, Inc. 2019-08-02
NCT03584594 Presepsin in the Diagnosis of Sepsis in Critically Ill Patients https://ClinicalTrials.gov/show/NCT03584594 Recruiting University Hospital Ostrava 2021-12-31
NCT03578978 A Panel of Biomarkers in Diagnosing Late-onset Neonatal Sepsis and Necrotizing Enterocolitis in Sibu Hospital https://ClinicalTrials.gov/show/NCT03578978 Recruiting Clinical Research Centre, Malaysia 2020-05-31
NCT03540797 Myeloid-derived Suppressor Cells in Sepsis https://ClinicalTrials.gov/show/NCT03540797 Recruiting Chang Gung Memorial Hospital 2023-12-31
NCT03506152 Evaluation of Serum Procalcitonin in Critically Ill Patients With Suspected Sepsis https://ClinicalTrials.gov/show/NCT03506152 Completed Aga Khan University 2015-12-03
NCT03489447 Mortality of Sepsis in Swedish Intensive Care Units 2008-2016 https://ClinicalTrials.gov/show/NCT03489447 Completed Uppsala University 2017-10-25
NCT03474809 Early Diagnostic of Sepsis and Potential Impact on Antibiotic Management Based on Serial.Pancreatic Stone Protein (PSP) Measured Using the AbioScope. https://ClinicalTrials.gov/show/NCT03474809 Completed Abionic SA 2019-03-15
NCT03433846 Predictors of Sepsis in Ex-Preterm Infants https://ClinicalTrials.gov/show/NCT03433846 Recruiting Boston Children’s Hospital 2020-04-01
NCT01236703 Hematological Infection Score Compared to the Hospital Standard for Diagnosis of SIRS or Sepsis on ICU https://ClinicalTrials.gov/show/NCT01236703 Completed Charite University, Berlin, Germany 2010-05-31
NCT01128283 Indicators of Inflammation and Coagulation in Sepsis https://ClinicalTrials.gov/show/NCT01128283 Completed University of Oklahoma 2014-05-31
NCT01120678 Improved Detection of Neonatal Sepsis Using a Targeted Biomarker Assay https://ClinicalTrials.gov/show/NCT01120678 Completed University of Virginia 2010-07-31
NCT01029080 Cerebrovascular Autoregulation During Sepsis https://ClinicalTrials.gov/show/NCT01029080 Completed Johannes Gutenberg University Mainz 2010-12-31
NCT01012115 Coagulation Factors, Cytokines and Tissue Injury Markers in Sepsis https://ClinicalTrials.gov/show/NCT01012115 Completed University of Oklahoma 2011-09-30
NCT00874367 Early-Onset Sepsis Surveillance Study https://ClinicalTrials.gov/show/NCT00874367 Completed NICHD Neonatal Research Network 2009-12-31
NCT00862290 Circulating microRNAs as Biomarkers of Sepsis https://ClinicalTrials.gov/show/NCT00862290 Completed Changhai Hospital 2009-04-30
NCT03780712 Immune Dysfunction in Newborn Sepsis https://ClinicalTrials.gov/show/NCT03780712 Completed BioMérieux 2018-03-12
NCT01392508 IMproved PREdiction of Severe Sepsis in the Emergency Department https://ClinicalTrials.gov/show/NCT01392508 Completed Axis Shield Diagnostics Ltd 2015-09-30
NCT00835913 Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis Impact https://ClinicalTrials.gov/show/NCT00835913 Completed University Hospital, Grenoble 2011-09-30
NCT03727243 Molecular Diagnosis and Risk Stratification of Sepsis in India https://ClinicalTrials.gov/show/NCT03727243 Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2020-07-31
NCT03201679 The Association Between Preoperative Sepsis and the Mortality After Hip Fracture Surgery https://ClinicalTrials.gov/show/NCT03201679 Completed Bispebjerg Hospital 2015-01-30
NCT00811629 Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients https://ClinicalTrials.gov/show/NCT00811629 Completed University Hospital, Clermont-Ferrand 2009-07-31
NCT01362504 Pro-adrenomedullin as a Prognostic Marker in Neonatal Sepsis https://ClinicalTrials.gov/show/NCT01362504 Completed Zekai Tahir Burak Women’s Health Research and Education Hospital 2011-08-31
NCT04026035 PCR Technic Evaluation in the Microbial Diagnostic of Septicemia in Hemodialysis Patients With Catheter. https://ClinicalTrials.gov/show/NCT04026035 Completed University Hospital, Bordeaux 2020-03-05
NCT03379402 Sepsis-3 Study in Northeast Thailand https://ClinicalTrials.gov/show/NCT03379402 Recruiting University of Oxford 2020-06-30
NCT02883218 Dynamic Alterations of Th2/Th1 With New Onset of Community-acquired Severe Sepsis Patients https://ClinicalTrials.gov/show/NCT02883218 Completed Southeast University, China 2018-07-20
NCT02170233 SHOCK US STUDY: Fluid Responsiveness in Sepsis Measured by Ultrasonography https://ClinicalTrials.gov/show/NCT02170233 Completed Yale University 2016-06-30
NCT02052895 Utility of Presepsin in Distinguishing Between Sepsis and SIRS https://ClinicalTrials.gov/show/NCT02052895 Completed Mochida Pharmaceutical Company, Ltd. 2015-07-31
NCT04441944 TELEmedicine as an Intervention for Sepsis in Emergency Departments https://ClinicalTrials.gov/show/NCT04441944 Recruiting University of Iowa 2019-06-30
NCT03953404 POC SPLA2-IIA as a Biomarker for Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT03953404 Recruiting St. Luke’s Hospital, Pennsylvania 2020-04-30
NCT00793442 Endothelium in Severe Sepsis https://ClinicalTrials.gov/show/NCT00793442 Completed Beth Israel Deaconess Medical Center 2013-05-31
NCT00781040 Neutropenic Fever, Inflammatory Markers and Sepsis in Haematological Patients https://ClinicalTrials.gov/show/NCT00781040 Completed Kuopio University Hospital 2019-01-01
NCT00736723 NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock https://ClinicalTrials.gov/show/NCT00736723 Completed University of Ulm 2012-08-31
NCT00698048 Serial Vasopressin and Copeptin Levels in Children With Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00698048 Completed KK Women’s and Children’s Hospital 2011-12-31
NCT00615862 Relationship Between Alcohol Use Disorders and Cortisol Levels in Patients With Sepsis https://ClinicalTrials.gov/show/NCT00615862 Completed Virginia Commonwealth University 2009-05-31
NCT00561639 Benefit of SeptiFast Multiplex PCR in the Etiologic Diagnosis and Therapeutic Approach for Onco-hematology Patients Presenting Sepsis https://ClinicalTrials.gov/show/NCT00561639 Completed University Hospital, Grenoble NA
NCT00541827 Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis https://ClinicalTrials.gov/show/NCT00541827 Completed Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico 2011-08-31
NCT00488917 Sepsis, Endothelial Function, and Lipids in Critically Ill Patients With Liver Failure (the SELLIFA Study) https://ClinicalTrials.gov/show/NCT00488917 Completed Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2009-08-31
NCT00448968 The Utility of Ischemia Modified Albumin (IMA) in Sepsis https://ClinicalTrials.gov/show/NCT00448968 Completed Inverness Medical Innovations NA
NCT00005207 Renin and Prorenin in Pregnancy https://ClinicalTrials.gov/show/NCT00005207 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00229034 Effect of APC and Epo on the Inflammatory Response During Sepsis https://ClinicalTrials.gov/show/NCT00229034 Completed Lawson Health Research Institute 2010-12-31
NCT00185783 Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis https://ClinicalTrials.gov/show/NCT00185783 Completed Stanford University 2006-11-30
NCT00175526 Predicting Complications in Women With Toxaemia https://ClinicalTrials.gov/show/NCT00175526 Completed University of British Columbia 2010-12-31
NCT00005208 Regulation of Placental Vascular Reactivity in Pregnancy-induced Hypertension https://ClinicalTrials.gov/show/NCT00005208 Completed National Heart, Lung, and Blood Institute (NHLBI) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03158493 Assessment of qSOFA in the Latin America Sepsis Institute Database https://ClinicalTrials.gov/show/NCT03158493 Completed Federal University of São Paulo 2017-03-31
NCT03029039 Platelet-associated Inflammation in Severe Sepsis https://ClinicalTrials.gov/show/NCT03029039 Recruiting Centre Hospitalier Universitaire de Saint Etienne 2020-06-30
NCT02936232 Severe Sepsis and Septic Shock Registry https://ClinicalTrials.gov/show/NCT02936232 Recruiting Seoul National University Hospital 2022-03-31
NCT02605681 Midkine and ACE-Ang II Induced Endothelial Injury in Sepsis https://ClinicalTrials.gov/show/NCT02605681 Completed Southeast University, China 2018-03-31
NCT02238795 Sepsis-Associated Purpura Fulminans International Registry - Europe https://ClinicalTrials.gov/show/NCT02238795 Recruiting Jena University Hospital 2019-12-31
NCT02180009 Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis https://ClinicalTrials.gov/show/NCT02180009 Completed Chinese PLA General Hospital 2015-08-31
NCT02020174 The Preeclampsia Registry https://ClinicalTrials.gov/show/NCT02020174 Recruiting Preeclampsia Foundation 2030-05-31
NCT01947127 Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency Department https://ClinicalTrials.gov/show/NCT01947127 Completed Chulalongkorn University 2014-11-30
NCT04292431 Leukocyte MOrphology and CORticosteroids Response in SEPtic Patients (MOCORSEP) https://ClinicalTrials.gov/show/NCT04292431 Recruiting Beckman Coulter, Inc. 2020-06-30
NCT04226430 Effect of Cytosorb on Blood Levels of Inflammatory Biomarkers of Sepsis. https://ClinicalTrials.gov/show/NCT04226430 Completed University of Gaziantep 2017-06-30
NCT04203979 Sepsis: From Syndrome to Personalized Care https://ClinicalTrials.gov/show/NCT04203979 Recruiting Oslo University Hospital 2020-12-31
NCT04135274 Is Neutrophil to Lymphocyte Ratio a Prognostic Factor of Sepsis in Newborns With Operated Neural Tube Defects? https://ClinicalTrials.gov/show/NCT04135274 Completed Tepecik Training and Research Hospital 2018-12-30
NCT03996720 Early Identification and Effective Management of Pediatric Sepsis https://ClinicalTrials.gov/show/NCT03996720 Recruiting Children’s Hospital of Fudan University 2020-12-31
NCT03956043 Diagnostic Accuracy in Sepsis https://ClinicalTrials.gov/show/NCT03956043 Recruiting Oslo University Hospital 2021-05-15
NCT03943719 Clinical Impact of the FilmArray Blood Culture Identification Panel Performed on Positive Blood Cultures From Intensive Care Patients With Septicemia https://ClinicalTrials.gov/show/NCT03943719 Completed Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2017-12-31
NCT03923543 Is Neutrophil to Lymphocyte Ratio a Prognostic Factor of Sepsis in Newborns With Operated Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03923543 Completed Tepecik Training and Research Hospital 2018-12-31
NCT03883061 Mathematical Modeling and Risk Factor Analysis for Mortality of Sepsis https://ClinicalTrials.gov/show/NCT03883061 Recruiting Shanghai Tongji Hospital, Tongji University School of Medicine 2019-03-01
NCT03789838 Effect of Sepsis Response Team in the Emergency Department https://ClinicalTrials.gov/show/NCT03789838 Completed Oslo University Hospital 2018-05-15
NCT03634891 An Audit Study on Management of Neonates With Neonatal Sepsis Admitted to Asyut University Children Hospital https://ClinicalTrials.gov/show/NCT03634891 Recruiting Assiut University 2019-06-01
NCT03523169 Cerebral Oxygen Challenge of Passive Leg Raising Test in Sepsis https://ClinicalTrials.gov/show/NCT03523169 Completed Peking Union Medical College Hospital 2017-11-01
NCT04448951 Immune Homeostasis in Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT04448951 Recruiting Charles University, Czech Republic 2021-12-31